Thank you Dr. Katz. This simple graphic should hang on every wall, in every office, where medicine is practiced. Not only as a reminder to those that seek help but to those that seek to help. With over eight billion people on the face of this planet, why is it so hard to recognize that there is no "one size fits all" cure or treatment. Responsibility to one's self and responsibility to each patient, as an individual, could not be more glaring than this simple graphic. Thank you again for your care to bring real truth to the conversations around our health. Peace, love and understanding. Dave
Great point that a study’s result describes the average effect of the intervention. The unwritten/unsaid disclaimer should be “YMMV”.
This is one of the aspects about EBM that keeps me very humble. Take any hypothetical intervention with an ARR of 10%, and an NNT of 10….absolute blockbuster. Yet in 9 out of 10 people, it will still be a complete waste of time….and we have no way to tell who is which, a priori. But unless we get to a point of “precision” medicine, EBM will be the best we’ve got.
Very cool! I think figures are the often the best part of the reading and interpreting a manuscript! The variation is striking in the figures you have shown! My understanding is that measuring variation in individual treatment response (ie. demonstrating heterogeneity of treatment effects) requires more data from multiple cross-overs to tease out the components of treatment response variation. Stephen Senn has done a lot of great work in this area.
Great post. Love all sensible medicine weight loss posts. If it were simple as just a diet, we would’ve stumbled on it ages ago. Addiction is addiction and it’s not treated by the medical community. In med school I learned nothing about addiction. There is an answer- Overeaters anonymous. Friend of Bill W.
Fantastic! This really resonates.
Thank you Dr. Katz. This simple graphic should hang on every wall, in every office, where medicine is practiced. Not only as a reminder to those that seek help but to those that seek to help. With over eight billion people on the face of this planet, why is it so hard to recognize that there is no "one size fits all" cure or treatment. Responsibility to one's self and responsibility to each patient, as an individual, could not be more glaring than this simple graphic. Thank you again for your care to bring real truth to the conversations around our health. Peace, love and understanding. Dave
Great point that a study’s result describes the average effect of the intervention. The unwritten/unsaid disclaimer should be “YMMV”.
This is one of the aspects about EBM that keeps me very humble. Take any hypothetical intervention with an ARR of 10%, and an NNT of 10….absolute blockbuster. Yet in 9 out of 10 people, it will still be a complete waste of time….and we have no way to tell who is which, a priori. But unless we get to a point of “precision” medicine, EBM will be the best we’ve got.
Very cool! I think figures are the often the best part of the reading and interpreting a manuscript! The variation is striking in the figures you have shown! My understanding is that measuring variation in individual treatment response (ie. demonstrating heterogeneity of treatment effects) requires more data from multiple cross-overs to tease out the components of treatment response variation. Stephen Senn has done a lot of great work in this area.
Great post. Love all sensible medicine weight loss posts. If it were simple as just a diet, we would’ve stumbled on it ages ago. Addiction is addiction and it’s not treated by the medical community. In med school I learned nothing about addiction. There is an answer- Overeaters anonymous. Friend of Bill W.